{"id":2796,"date":"2025-10-23T13:39:58","date_gmt":"2025-10-23T11:39:58","guid":{"rendered":"https:\/\/biomol.es\/?p=2796"},"modified":"2025-10-23T13:49:52","modified_gmt":"2025-10-23T11:49:52","slug":"newsletter-biomol-inovacao-em-sequenciacao-e-proteomica-com-a-bgisolucoes-integrais-para-a-investigacao-biomedica","status":"publish","type":"post","link":"https:\/\/biomol.es\/pt-pt\/newsletter-biomol-inovacao-em-sequenciacao-e-proteomica-com-a-bgisolucoes-integrais-para-a-investigacao-biomedica\/","title":{"rendered":"Inova\u00e7\u00e3o em sequencia\u00e7\u00e3o e prote\u00f3mica com a BGI – Solu\u00e7\u00f5es integrais para a investiga\u00e7\u00e3o biom\u00e9dica"},"content":{"rendered":"\n

A Biomol, em colabora\u00e7\u00e3o com a BGI Genomics, disponibiliza a centros de investiga\u00e7\u00e3o, hospitais e empresas de biotecnologia um portef\u00f3lio completo de servi\u00e7os de sequencia\u00e7\u00e3o, an\u00e1lise multi-\u00f3mica e prote\u00f3mica de \u00faltima gera\u00e7\u00e3o. O objetivo desta colabora\u00e7\u00e3o \u00e9 simplificar os processos de comunica\u00e7\u00e3o e log\u00edstica\u2014facilitando tanto a prepara\u00e7\u00e3o como o envio de amostras\u2014para que as equipas cient\u00edficas se concentrem no essencial: gerar conhecimento.<\/p>\n\n\n\n

Com a tecnologia propriet\u00e1ria DNBSEQ\u2122, s\u00e3o oferecidas solu\u00e7\u00f5es com elevada precis\u00e3o, baixa taxa de erros e grande escalabilidade, adaptadas a projetos de qualquer dimens\u00e3o. A experi\u00eancia global da BGI\u2014com milh\u00f5es de amostras processadas em mais de 100 pa\u00edses e certifica\u00e7\u00f5es internacionais (CAP, CLIA, CE-IVD)\u2014sustenta a robustez destes servi\u00e7os.<\/p>\n\n\n\n

Amplo portef\u00f3lio de servi\u00e7os<\/strong><\/h2>\n\n\n\n

O acordo de colabora\u00e7\u00e3o entre a Biomol e a BGI Genomics permite oferecer um portef\u00f3lio integral que abrange desde a sequencia\u00e7\u00e3o de ADN e ARN at\u00e9 \u00e0 an\u00e1lise avan\u00e7ada de prote\u00ednas e metabolitos, com suporte bioinform\u00e1tico e acompanhamento t\u00e9cnico em cada fase do projeto.<\/p>\n\n\n\n

Esta oferta estrutura-se em duas linhas complementares:
\u2022 Solu\u00e7\u00f5es cl\u00ednicas, orientadas para o diagn\u00f3stico gen\u00e9tico e a medicina personalizada.
\u2022 Solu\u00e7\u00f5es tecnol\u00f3gicas, concebidas para investiga\u00e7\u00e3o gen\u00f3mica, transcript\u00f3mica, epigen\u00f3mica, prote\u00f3mica e multi-\u00f3mica.<\/p>\n\n\n\n

1) Solu\u00e7\u00f5es cl\u00ednicas<\/p>\n\n\n\n

As solu\u00e7\u00f5es cl\u00ednicas da Biomol e da BGI foram concebidas para apoiar a medicina personalizada, combinando sequencia\u00e7\u00e3o massiva e an\u00e1lise bioinform\u00e1tica de alta qualidade.<\/p>\n\n\n\n

\u00c1reas principais:
\u2022 Sa\u00fade reprodutiva: testes gen\u00e9ticos para portadores, rastreio pr\u00e9-natal e diagn\u00f3stico pr\u00e9-implantacional.
\u2022 Oncologia molecular: pain\u00e9is para cancro heredit\u00e1rio, perfil gen\u00f3mico tumoral e orienta\u00e7\u00e3o terap\u00eautica.
\u2022 Doen\u00e7as infeciosas: identifica\u00e7\u00e3o de pat\u00f3genos por sequencia\u00e7\u00e3o metagen\u00f3mica (PMseq) ou dirigida (PTseq).
\u2022 Gen\u00e9tica cl\u00ednica: estudos de exoma completo, genotipagem e variantes associadas a doen\u00e7as cr\u00f3nicas ou raras.<\/p>\n\n\n\n

Estas solu\u00e7\u00f5es aplicam a sequencia\u00e7\u00e3o de nova gera\u00e7\u00e3o (NGS) \u00e0 pr\u00e1tica cl\u00ednica, favorecendo o diagn\u00f3stico precoce, a estratifica\u00e7\u00e3o de doentes e decis\u00f5es terap\u00eauticas mais precisas.<\/p>\n\n\n\n

2) Solu\u00e7\u00f5es tecnol\u00f3gicas<\/p>\n\n\n\n

A BGI oferece uma das infraestruturas mais abrangentes a n\u00edvel mundial para sequencia\u00e7\u00e3o, prote\u00f3mica e an\u00e1lise multi-\u00f3mica, cobrindo todas as fases do fluxo experimental, desde a extra\u00e7\u00e3o at\u00e9 \u00e0 an\u00e1lise avan\u00e7ada de dados.<\/p>\n\n\n\n

Servi\u00e7os de sequencia\u00e7\u00e3o<\/strong><\/h2>\n\n\n\n


\u2022 Gen\u00f3mica e exoma: whole genome resequencing, de novo sequencing, bisulfite sequencing, ChIP-seq, exome capture.
\u2022 Transcript\u00f3mica (RNA-seq): mRNA, long non-coding RNA, small RNA, isoform sequencing e estudos strand-specific.
\u2022 Metagen\u00f3mica e microbioma: caracteriza\u00e7\u00e3o microbiana por 16S\/18S\/ITS e shotgun metagenomics.
\u2022 Epigen\u00f3mica: an\u00e1lises de metila\u00e7\u00e3o e regula\u00e7\u00e3o g\u00e9nica.
\u2022 Single-cell e spatial omics: resolu\u00e7\u00e3o celular e espacial para transcript\u00f3mica e epigen\u00e9tica.<\/p>\n\n\n\n

Prote\u00f3mica e metabol\u00f3mica<\/strong><\/h2>\n\n\n\n


A prote\u00f3mica, baseada em espectrometria de massas, permite quantificar e caracterizar milhares de prote\u00ednas em simult\u00e2neo, identificar modifica\u00e7\u00f5es p\u00f3s-traducionais (PTM) e analisar redes funcionais.<\/p>\n\n\n\n

Os servi\u00e7os incluem:
\u2022 Prote\u00f3mica quantitativa (label-free, DIA, TMT).
\u2022 Prote\u00f3mica dirigida e nanoprote\u00f3mica.
\u2022 Combina\u00e7\u00f5es multi-\u00f3micas: integra\u00e7\u00e3o de prote\u00f3mica com transcript\u00f3mica e metabol\u00f3mica para uma vis\u00e3o global dos processos biol\u00f3gicos.<\/p>\n\n\n\n

A prote\u00f3mica \u00e9 um dos pilares da oferta, permitindo caracterizar express\u00e3o, abund\u00e2ncia, intera\u00e7\u00f5es e modifica\u00e7\u00f5es proteicas em organismos, tecidos ou c\u00e9lulas.<\/p>\n\n\n\n

Em conjunto com dados de gen\u00f3mica e transcript\u00f3mica, a prote\u00f3mica fornece um mapa biol\u00f3gico integrado que impulsiona avan\u00e7os em:
\u2022 Medicina personalizada
\u2022 Oncologia molecular
\u2022 Doen\u00e7as raras
\u2022 Neuroci\u00eancia
\u2022 Microbioma humano e ambiental
\u2022 Biologia do desenvolvimento
\u2022 Farmacogen\u00f3mica<\/p>\n\n\n\n

An\u00e1lise bioinform\u00e1tica e visualiza\u00e7\u00e3o de dados<\/h2>\n\n\n\n

Todos os servi\u00e7os s\u00e3o suportados por plataformas bioinform\u00e1ticas especializadas e ferramentas de interpreta\u00e7\u00e3o como o Dr. Tom<\/strong>, que permitem ao investigador aceder a resultados claros, comparativos e prontos para publica\u00e7\u00e3o.<\/p>\n\n\n\n

As equipas de an\u00e1lise da BGI oferecem suporte em alinhamento, quantifica\u00e7\u00e3o, dete\u00e7\u00e3o de variantes, an\u00e1lise diferencial e enriquecimento funcional, assegurando a m\u00e1xima rastreabilidade dos dados.<\/p>\n\n\n\n

Benef\u00edcios-chave oferecidos pela BGI<\/h2>\n\n\n\n

\u2022 Elevada precis\u00e3o e baixa taxa de duplicados.
\u2022 Certifica\u00e7\u00f5es internacionais: CAP, CLIA, CE-IVD<\/strong>.
\u2022 Otimiza\u00e7\u00e3o de custos e escalabilidade para projetos grandes ou pequenos.
\u2022 Suporte t\u00e9cnico integral: desenho experimental, extra\u00e7\u00e3o, sequencia\u00e7\u00e3o e an\u00e1lise bioinform\u00e1tica.
\u2022 Ampla gama de aplica\u00e7\u00f5es: projetos em humanos, animais, plantas e microrganismos.
\u2022 Infraestrutura tecnol\u00f3gica diversificada: gen\u00f3mica, transcript\u00f3mica, epigen\u00f3mica, prote\u00f3mica e metabol\u00f3mica.<\/p>\n\n\n\n

Um parceiro estrat\u00e9gico para cada fase<\/h2>\n\n\n\n

A Biomol posiciona-se como um aliado estrat\u00e9gico em todas as fases do projeto. Do desenho do estudo \u00e0 rece\u00e7\u00e3o dos resultados, \u00e9 oferecido um acompanhamento cont\u00ednuo e personalizado.<\/p>\n\n\n\n

Gra\u00e7as \u00e0 integra\u00e7\u00e3o de gen\u00f3mica, transcript\u00f3mica, epigen\u00f3mica, prote\u00f3mica e metabol\u00f3mica, \u00e9 facilitada uma vis\u00e3o global dos processos biol\u00f3gicos, gerando conhecimento aplic\u00e1vel \u00e0 descoberta de novos biomarcadores, terapias inovadoras e ferramentas de diagn\u00f3stico.<\/p>\n\n\n\n

O compromisso conjunto \u00e9 disponibilizar solu\u00e7\u00f5es cient\u00edficas de elevada qualidade que impulsionem o progresso na investiga\u00e7\u00e3o b\u00e1sica, aplicada e translacional.<\/p>\n","protected":false},"excerpt":{"rendered":"

A Biomol, em colabora\u00e7\u00e3o com a BGI Genomics, disponibiliza a centros de investiga\u00e7\u00e3o, hospitais e empresas de biotecnologia um portef\u00f3lio completo de servi\u00e7os de sequencia\u00e7\u00e3o, an\u00e1lise multi-\u00f3mica e prote\u00f3mica de \u00faltima gera\u00e7\u00e3o. O objetivo desta colabora\u00e7\u00e3o \u00e9 simplificar os processos de comunica\u00e7\u00e3o e log\u00edstica\u2014facilitando tanto a prepara\u00e7\u00e3o como o envio de amostras\u2014para que as equipas …<\/p>\n","protected":false},"author":12,"featured_media":2797,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[38,51],"tags":[],"class_list":["post-2796","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biomedicina-pt-pt","category-ngs-3"],"acf":[],"yoast_head":"\nInova\u00e7\u00e3o em sequencia\u00e7\u00e3o e prote\u00f3mica com a BGI - Solu\u00e7\u00f5es integrais para a investiga\u00e7\u00e3o biom\u00e9dica - Biomol<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/biomol.es\/pt-pt\/newsletter-biomol-inovacao-em-sequenciacao-e-proteomica-com-a-bgisolucoes-integrais-para-a-investigacao-biomedica\/\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Inova\u00e7\u00e3o em sequencia\u00e7\u00e3o e prote\u00f3mica com a BGI - Solu\u00e7\u00f5es integrais para a investiga\u00e7\u00e3o biom\u00e9dica - Biomol\" \/>\n<meta property=\"og:description\" content=\"A Biomol, em colabora\u00e7\u00e3o com a BGI Genomics, disponibiliza a centros de investiga\u00e7\u00e3o, hospitais e empresas de biotecnologia um portef\u00f3lio completo de servi\u00e7os de sequencia\u00e7\u00e3o, an\u00e1lise multi-\u00f3mica e prote\u00f3mica de \u00faltima gera\u00e7\u00e3o. O objetivo desta colabora\u00e7\u00e3o \u00e9 simplificar os processos de comunica\u00e7\u00e3o e log\u00edstica\u2014facilitando tanto a prepara\u00e7\u00e3o como o envio de amostras\u2014para que as equipas …\" \/>\n<meta property=\"og:url\" content=\"https:\/\/biomol.es\/pt-pt\/newsletter-biomol-inovacao-em-sequenciacao-e-proteomica-com-a-bgisolucoes-integrais-para-a-investigacao-biomedica\/\" \/>\n<meta property=\"og:site_name\" content=\"Biomol\" \/>\n<meta property=\"article:published_time\" content=\"2025-10-23T11:39:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-10-23T11:49:52+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/biomol.es\/wp-content\/uploads\/2025\/10\/Captura-de-pantalla-29-2.png\" \/>\n\t<meta property=\"og:image:width\" content=\"695\" \/>\n\t<meta property=\"og:image:height\" content=\"392\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Biomol Admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@_Biomol_\" \/>\n<meta name=\"twitter:site\" content=\"@_Biomol_\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Biomol Admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo estimado de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/biomol.es\/pt-pt\/newsletter-biomol-inovacao-em-sequenciacao-e-proteomica-com-a-bgisolucoes-integrais-para-a-investigacao-biomedica\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/biomol.es\/pt-pt\/newsletter-biomol-inovacao-em-sequenciacao-e-proteomica-com-a-bgisolucoes-integrais-para-a-investigacao-biomedica\/\"},\"author\":{\"name\":\"Biomol Admin\",\"@id\":\"https:\/\/biomol.es\/pt-pt\/#\/schema\/person\/fc7ce18426ed3c487451b87dd9f599d6\"},\"headline\":\"Inova\u00e7\u00e3o em sequencia\u00e7\u00e3o e prote\u00f3mica com a BGI – Solu\u00e7\u00f5es integrais para a investiga\u00e7\u00e3o biom\u00e9dica\",\"datePublished\":\"2025-10-23T11:39:58+00:00\",\"dateModified\":\"2025-10-23T11:49:52+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/biomol.es\/pt-pt\/newsletter-biomol-inovacao-em-sequenciacao-e-proteomica-com-a-bgisolucoes-integrais-para-a-investigacao-biomedica\/\"},\"wordCount\":898,\"publisher\":{\"@id\":\"https:\/\/biomol.es\/pt-pt\/#organization\"},\"image\":{\"@id\":\"https:\/\/biomol.es\/pt-pt\/newsletter-biomol-inovacao-em-sequenciacao-e-proteomica-com-a-bgisolucoes-integrais-para-a-investigacao-biomedica\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/biomol.es\/wp-content\/uploads\/2025\/10\/Captura-de-pantalla-29-2.png\",\"articleSection\":[\"Biomedicina\",\"NGS\"],\"inLanguage\":\"pt-PT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/biomol.es\/pt-pt\/newsletter-biomol-inovacao-em-sequenciacao-e-proteomica-com-a-bgisolucoes-integrais-para-a-investigacao-biomedica\/\",\"url\":\"https:\/\/biomol.es\/pt-pt\/newsletter-biomol-inovacao-em-sequenciacao-e-proteomica-com-a-bgisolucoes-integrais-para-a-investigacao-biomedica\/\",\"name\":\"Inova\u00e7\u00e3o em sequencia\u00e7\u00e3o e prote\u00f3mica com a BGI - 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